LMU professors Kam Dahlquist, a biology professor, and Ben Fitzpatrick, a math professor, have received a $250,000 grant to construct a mathematical model that will allow scientists to predict how genes change their regulation in different environments. The professors will be using the National Science Foundation grant to examine how networks of genes are regulated in baker’s yeast, which has similar characteristics to human cells.
In an collaboration of specialties, Dahlquist and Fitzpatrick have spent the last three years working on a model that will predict how cells behave. Their research entails use of mathematical modeling and genomics techniques, which allows scientists to study thousands of genes at a time.
“I am pleased that the grant Ben and I received will enable us to extend our collaborative research into how genes interact in different environments, which may lead to a better understanding of complex genetic diseases.”
LMU students will play a key role in conducting the research and for the next three years students will work side by side with the professors.
The researchers have three goals: to create an accurate model that predicts gene regulation; to develop cutting edge mathematic techniques that can be applied to other research areas; and learn new information on how yeast responds to environmental stress. The researchers hope their findings will provide them with a closer understanding of diseases such as type 2 diabetes.